GROUP MEMBERS

CAROLINE LEI WEE

Principal Investigator

Ph.D.  in Neurobiology, Harvard Medical School, Boston, MA (2016)

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B.A.  Cornell University, College of Arts and Sciences, Ithaca, NY (2009)

Double Major in Biological Sciences (Neurobiology and Behavior) & Psychology 

Distinction in all subjects

Summa cum laude

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Caroline's research interest is in understanding the fundamental mechanisms governing motivated behaviors such as feeding and stress, with the goal of improving human health and well-being. Towards this goal, she has won several significant fellowships and grants, including the A*STAR National Science Scholarship (NSS BS-PhD, 2006, 2010), National Medical Research Council Young Individual Research Grant (2020) and National Research Foundation Fellowship (Class of 2021). She is also a lead Principal Investigator in A*STAR's Brain-Body Initiative. 

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Personal Website 

LinkedIn

RUEY-KUANG CHENG

Senior Research Fellow

Ph.D. in Neuroscience, Duke University, Durham, North Carolina (2010)

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M.S. National Cheng-Chi University, Taipei, Taiwan (2002)

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B.S. National Cheng-Chi University, Taipei, Taiwan (1999)

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Ruey has more than 10 years of experience in both zebrafish and rodent behavioral neuroscience research, and trained in the lab of Dr. Suresh Jesuthasan (NTU-LKC, Singapore). His expertise includes behavioral and in vivo calcium imaging, electrophysiology, and hardware/software development for animal behavior analysis. His research interests include timing and time perception, learning and memory, decision making, and emotional control of behavior.

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Research Gate

Google Scholar

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VINDHYA CHAGANTY

Research Fellow

Ph.D. in Developmental biology, National University of Singapore (2021)

M.Sc. Biotechnology V.I.T University, India (2016)

B.Sc. Biotechnology V.I.T University, India (2014)

During her Ph.D., Vindhya used zebrafish as a model organism to study neurodegenerative diseases. Her current research interest is in understanding the neural circuitry and genetics of appetite control. Her expertise includes microscopy, behavioral analysis, and transcriptomics.

WEN LIE

PhD Candidate

A*STAR Graduate Scholarship (Singapore) (2021)

Pharmacist, Singapore Pharmacy Council (2021)

B.Sc. (Pharmacy) with Honours (Highest Distinction), National University of Singapore (2020)

Research Experience:

• Developed a mammalian expression system expressing SARS-CoV-2 proteins for production of virus-like particles

• Investigated the metabolizing enzymes and disposition kinetics of two synthetic cannabinoids and their metabolites 

Research Interests:

• Gut microbiome

• Drug metabolism and pharmacokinetics

LinkedIn

YEO HUI LI

Research Officer (Biology)

B.S. (Hons) in Biotechnology, First Class Honours, Northumbria University (2016)

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Hui Li trained in the lab of Dr. Sudipto Roy (IMCB). She has more than 4 years of zebrafish research experience and extensive expertise in molecular biology, genetics, and microscopy. She also manages daily lab operations. 

GUAN ZHEN

Research Officer (Software Engineering)

Co-supervised by Dr. Cheng Li (Assoc. Prof., University of Alberta, Adjunct Prof., Bioinformatics Institute A*STAR)

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B.Sc. in Mathematical Sciences (Statistics), Nanyang Technological University, Singapore

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Past projects:

• Collaborated with Dr Huang Weimin’s team from I2R (A*STAR) and GE Japan on segmenting coronary artery from 3D heart CT images. Developed a reconstruction algorithm which improves recall, precision and f1 score by 9.5%, 1.6% and 5% respectively.

Research interests:

• Machine/deep learning application on biomedical data

• Action recognition & action detection

GAYNAH DOBLADO

Laboratory Officer (Biology)

Diploma in Marine Science and Aquaculture, Republic Polytechnic, Singapore (2021)

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Research Experience:

• Intern at the Environmental Engineering cluster in Singapore Centre for Environmental Life Sciences Engineering (SCELSE), under the integrated theme of Marine Biofilms & Microbiomes. 

• Research study under Dr Grace Loo to investigate presence of genetic markers in shrimps.

Research Interests:

• Genetics and Marine Biology

JAZLYNN TAN

Research Officer (Biology)

B.Sc. in Biological Sciences, First Class Honours, Imperial College London (2021)

A*STAR NSS (BS) Scholarship (2018)

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Research Experience:

• Automated quantification of fungal burden from histological images of lung tissue infected with Aspergillus fumigatus 

• Bioinformatics study on using cell-free DNA fragment data for cancer detection and tumour burden quantification

Research interests:

• Biological imaging, medical imaging

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LinkedIn

CHUA KAI XIN

Research Officer (Biology)

B.S. in Business and Environmental Sciences, Majoring in Aquaculture, James Cook University Singapore (2020)

Research Experience:

• Research on ciliopathies using zebrafish and mice as animal models

• Population Dynamics and Phylogenetic Analysis of Canine Parvovirus

Research interests:

• Physiology of eating disorders and mental health

CHERYL TAN

Research Officer (Biology)
Previously Research Assistant (SGUnited Traineeship)

B.Sc. (Hons) in Pharmacology, Newcastle University, UK (2020)

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Research Experience:

• University summer placement at NTU [GEM Trailblazer Research Programme] aiding Research Fellow Dr. Serafino Teseo in investigating the effect of gut microbes on the eusocial behavior of ants

• Thesis under Professor Jonathan MG Higgins and Dr. Tyrell Cartwright investigating role of VRK1 in Histone H3 phosphorylation

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Research Interests:

• Drug interactions and drug resistance

DINAH YUSOFF

Research Assistant (SGUnited Traineeship)

B.Sc. in Pharmacology, Monash University, Australia (2020)

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Research experience:

• Tableting trials to determine appropriate quality parameters for Diana Food (nutraceutical)

• Handling of mice in effects of centrally acting drugs on mice behaviour, and neurological and autonomic functions under the Department of Pharmacology, Monash University

Research interests:

• Drug interactions and Neuropharmacology