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GROUP MEMBERS

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CAROLINE LEI WEE

Principal Scientist II (Principal Investigator)

Adjunct Assistant Professor, Department of Physiology, National University of Singapore (NUS)

Ph.D. in Neurobiology, Harvard Medical School, Boston, MA (2016)

B.A. Cornell University, College of Arts and Sciences, Ithaca, NY (2009)

    Double Major in Biological Sciences (Neurobiology and Behavior) & Psychology 

    Distinction in all subjects

    Summa cum laude

A*STAR NSS (BS-PhD) Scholarship (2006, 2010)

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Caroline's research interest is in understanding the fundamental mechanisms governing motivated behaviors such as feeding and stress, with the goal of improving human health and well-being. Towards this goal, she has won several significant fellowships and grants, including the A*STAR National Science Scholarship (NSS BS-PhD, 2006, 2010), National Medical Research Council Young Individual Research Grant (2020) and National Research Foundation Fellowship (Class of 2021). She is also a lead Principal Investigator in A*STAR's Brain-Body Initiative. 

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Personal Website 

LinkedIn

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RUEY-KUANG CHENG

Senior Scientist 

Ph.D. in Neuroscience, Duke University, Durham, North Carolina (2010)

M.S. National Cheng-Chi University, Taipei, Taiwan (2002)

B.S. National Cheng-Chi University, Taipei, Taiwan (1999)

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Ruey has more than 10 years of experience in both zebrafish and rodent behavioral neuroscience research, and trained in the lab of Dr. Suresh Jesuthasan (NTU-LKC, Singapore). His expertise includes behavioral and in vivo calcium imaging, electrophysiology, and hardware/software development for animal behavior analysis. His research interests include timing and time perception, learning and memory, decision making, and emotional control of behavior.

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Research Gate

Google Scholar

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VINDHYA CHAGANTY

Scientist 

Ph.D. in Developmental biology, National University of Singapore (2021)

M.Sc. Biotechnology V.I.T University, India (2016)

B.Sc. Biotechnology V.I.T University, India (2014)


During her Ph.D., Vindhya used zebrafish as a model organism to study neurodegenerative diseases. Her current research interest is in understanding the neural circuitry and genetics of appetite control. Her expertise includes microscopy, behavioral analysis, and transcriptomics.

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JING-XUAN LIM

Scientist 

Ph.D. in Neuroscience, John's Hopkins School of Medicine, Baltimore, MD

B.Sc. in Neuroscience, University College London 

A*STAR NSS (BS-PhD) Scholarship

 

During his PhD, Jing-Xuan investigated how behavioral states influence information processing in the larval zebrafish. In the lab, Jing-Xuan is interested in applying quantitative approaches for the analysis of high-dimensional neuroimaging and behavioral data.

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XIAOYAN YUE

Scientist 

Ph.D. in Pomology, Zhejiang University, Hangzhou, China (2018)
B.S. in Horticulture, Sichuan Agriculture University, Ya’an, China (2011)

 

Xiaoyan has experience in analysing various types of Genomic and Transcriptomic datasets from her Ph.D. and postdoctoral training. Her current research interests include big data analysis, with a particular passion for integrating computational tools to derive meaningful insights from diverse datasets.

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EUGENE LEE

Scientist 

Ph.D. in Brain and Cognitive Sciences, MIT, Boston, MA (2023)
B.S. in Biomedical Sciences, Imperial College London, UK (2013)

A*STAR NSS (BS-PhD) Scholarship (2006, 2010)

 

Eugene is interested in a mechanistic understanding of bidirectional interactions between the brain and reproductive system across biological scales and how they impact organismal physiology and health. His PhD studies were focused on learning and temporal pattern processing by the nematode C. elegans.

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WEN LIE

PhD Student (joint with Prof. Eric Chan)

A*STAR Graduate Scholarship (Singapore) (2021)

Pharmacist, Singapore Pharmacy Council (2021)

B.Sc. (Pharmacy) with Honours (Highest Distinction), National University of Singapore (2020)

 

Research Experience:

  • Developed a mammalian expression system expressing SARS-CoV-2 proteins for production of virus-like particles

  • Investigated the metabolizing enzymes and disposition kinetics of two synthetic cannabinoids and their metabolites 

 

Research Interests:

  • Gut microbiome

  • Drug metabolism and pharmacokinetics

 

LinkedIn

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TERUMI NAKASHIMA

PhD Student (Joint with Assoc. Prof. Ajay Mathuru)

Singapore International Graduate Award (SINGA) Scholarship (2023)

M.S. in Microbiology and Parasitology, Universidade Federal Fluminense (2021)

B.S. in Biomedical Sciences, Universidade Federal Fluminense (2018)

 

My previous research experience was to perform diagnosis of parasitic diseases in children in Brazil, focusing on gastrointestinal parasites. During my Master's Degree, I conducted a systematic review and meta analysis on the prevalence of Cryptosporidium species in animals in Latin America

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My current research interest is to understand neuroimmune interactions.

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LYNETTE LIM

PhD Student (Joint with Assoc. Prof Shuo-Chien Ling)

A*STAR Graduate Scholarship (Singapore) (2024)

B.Sc. (Life Science) with Honours (Distinction), National University of Singapore (2018)

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My final year undergraduate thesis focused on neuroinflammation and neurometabolism. I then joined the Singapore Institute of Food and Biotechnology Innovation as a Research Officer in 2022. There, I shifted to food science and biotechnology, in the cluster of fungal engineering for alternative protein production, and set up CRISPR-based diagnostic tools for assessing risks in novel foods. Currently, my PhD research explores the impact of nutrition on the gut-brain axis and its therapeutic potential on neurodegenerative diseases using the zebrafish model.​​

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LinkedIn

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KHEI MIN LEONG

Singapore International Graduate Award (SINGA) Scholarship (2025)

B.Sc. of Biomedical Science, University of Putra Malaysia (2024), First Class Honours​

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Research Experience: 

Investigating the effects of postbiotics on cervical cancer cell lines using vaginal-isolated probiotics

 

Research Interests:

  • Gut microbiome 

  • Liver-brain axis

  • Metabolic disease​​​​​

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GAYNAH DOBLADO

Research Officer 

B.S. in Aquaculture Science and Technology, James Cook University Singapore (2024)  

Diploma in Marine Science and Aquaculture, Republic Polytechnic (2021)

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Research Experience:

  • Intern at the Environmental Engineering cluster in Singapore Centre for Environmental Life Sciences Engineering (SCELSE), under the integrated theme of Marine Biofilms & Microbiomes. 

  • Research study under Dr Grace Loo to investigate presence of genetic markers in shrimps.

 

Research Interests:

  • Genetics and Marine Biology

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CHUA KAI XIN

Research Officer

B.S. in Business and Environmental Sciences, Majoring in Aquaculture, James Cook University Singapore (2020)

 

Research Experience:

  • Research on ciliopathies using zebrafish and mice as animal models

  • Population Dynamics and Phylogenetic Analysis of Canine Parvovirus

 

Research Interests:

  • Physiology of eating disorders and mental health

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DINAH YUSOFF

Research Officer 
Previously Research Assistant (SGUnited Traineeship)

B.Sc. in Pharmacology, Monash University, Australia (2020)

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Research Experience:

  • Tableting trials to determine appropriate quality parameters for Diana Food (nutraceutical)

  • Handling of mice in effects of centrally acting drugs on mice behaviour, and neurological and autonomic functions under the Department of Pharmacology, Monash University

 

Research Interests:

  • Drug interactions and Neuropharmacology

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VALARIE THAM

Research Officer

B.Sc. in Molecular Biology, La Trobe University (2018) 

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Research Experience:

  • Final Year Project in collaboration with National University of Singapore on the Optimization of a Diagnostic Platform for Dengue, Chikungunya and Zika 

  • Research in Genome Institute of Singapore that targets Metabolic Vulnerabilities in Liver Cancer 


Research Interests:

  • Genetics and Neuromuscular Diseases

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AFSHA NESHA

Research Officer

B.Sc. (Hons) in Biomedical Science, Specialised in Medical Biochemistry, University of Bradford (UK) affiliated with MDIS Singapore (2015)

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Nesha became interested in research when she was in A*STAR's Biological Resource Centre, handling and working on lab animals. She has also gained lab experience and skills from working in medical laboratories. Her previous research experience in Dr Adrian Teo’s lab focused on increasing the proliferation rate of insulin-producing pancreatic beta cells isolated from rodents and humans.

 

Her current research interests are in Genetics and Toxicology. 

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SUMMER LI

Research Officer (Joint with Sarah Luo lab)

B.Sc. in Biological Sciences, Imperial College London, Department of Life Sciences, London, UK (2024)

    First Class Honours

A*STAR NSS (BS-PhD) Scholarship (2021)

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Research Experience:

  • Investigated the role of Dally and GPC3 glypicans in the JAK/STAT signalling pathway and how they influence gut regeneration in Drosophila at the Francis Crick Institute under Professor Jean-Paul Vincent

  • Investigated the role of Foxj1 in the development of olfactory sensory neurons in zebrafish, and the role of geminin in the differentiation of multiciliated cells, with Dr Sudipto Roy 

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Research Interests:

  • Effects of the peripheral nervous system on diseases

  • Animal behavioural studies

  • Microbiota-gut-brain axis 

MASTER'S STUDENTS

SEE ALUMNI SECTION

INTERNS

CRYSTAL LEE (NUS, A*STAR RESEARCH INTERNSHIP AWARDEE, FINAL YEAR PROJECT STUDENT)

PHAM HOAI BAO (SINGAPORE INTERNATIONAL PRE-GRADUATE AWARDEE (SIPGA), VIETNAM NATIONAL UNIVERSITY)

VIONA SETIAWAN (SINGAPORE INTERNATIONAL PRE-GRADUATE AWARDEE (SIPGA), BANDUNG INSTITUTE OF TECHNOLOGY)

AVELYNN ANG (NTU, A*STAR RESEARCH INTERNSHIP AWARDEE)

KATELYN YIP (POST-JC ATTACHMENT)

JOVIAN LIN (NTU, CW LAB ALUMNA)

ALUMNI (STAFF & STUDENTS)

SASMITHA SINGH

Graduated with MSc. in Biotechnology, NUS

GUAN ZHEN

Senior Research Officer
Currently Data Scientist at Risk Lighthouse

SANDRA TAN

Research Officer
A*STAR NSS (BS) scholar
Currently pursuing a PhD on A*STAR NSS (PhD) scholarship

JOVIAN LIN

Laboratory Officer
Admitted to Nanyang Technological University

HUI LI YEO

Senior Research Officer
Currently Project Manager in ESCAR Lab

JOLIN TAN

Laboratory Officer (Aquaculture)
Admitted to the University of Queensland

PHOEBE TAN

Research Officer
Transferred to Leslie Beh Lab (IMCB)

FENGLIN LI

Graduated with Msc in Food Science and Human Nutrition, National University of Singapore

DINGMING CHEN

Graduated with Msc in Food Science and Human Nutrition, National University of Singapore

JAZLYNN TAN

Research Officer
A*STAR NSS (BS) scholar
Currently pursuing a PhD on A*STAR NSS (PhD) scholarship

CHERYL TAN

Research Officer (previously on SGUnited Traineeship) 
Currently pursuing a Masters at the National University of Singapore

ALUMNI (INTERNS)

MARIT TE WALVAART 
Nord University, now Completing Master's Research 

JIAWEI (CLEO) YU 
King's College London

CHRISTIAAN STARKE
Cardiff University, A*STAR Research Internship Awardee

ELYSE KHOO
Singapore Polytechnic, now Laboratory Officer with Sarah Luo Lab

TOM LEE

National University of Singapore, A*STAR Research Internship Awardee

QING YA FANG (CELEST)

Ngee Ann Polytechnic, A*STAR Science Awardee

SEAN PHANG

Nanyang Technological University, A*STAR Research Internship Awardee & Final Year Project Student

ASHLEY ANAND

University of Bristol

DEVIN TANG

Singapore Institute of Technology (Integrated Work Study Programme)

DARREN LAM

National University of Singapore, A*STAR Research Internship Awardee & Final Year Project Student 

IGNATIUS HWANG-SHIN

National University of Singapore, A*STAR Research Internship Awardee

JENNY ZHANG & YU XIN TAN

National University of Singapore (Pharmacy), Final Year Project Students

BECKHAM KANG KUAN YUAN

Singapore Polytechnic

KENNETH SUHARDJO

Anglo-Chinese Junior College, SSEF Bronze Medalist

KAI LIN CHUA

National University of Singapore

KELLIE WONG

National University of Singapore, A*STAR Research Internship Awardee

WEE LENG TAN

National University of Singapore, A*STAR Research Internship Awardee & Final Year Project Student

CHLOE LIN

Singapore Polytechnic, A*STAR Science Awardee
Currently in National University of Singapore (School of Medicine)

RYAN ANG

Singapore Polytechnic, A*STAR Science Awardee

XIPING LE

H3 Programme Student (Hwa Chong Institution) and SSEF Gold Medalist

YUCHENG JIN

H3 Programme Student (Victoria Junior College) and SSEF Silver Medalist

DANIAL ASRI

SGUnited Traineeship

JERRICK KWAN

Republic Polytechnic, A*STAR Science Awardee

JERRYL TAN

Republic Polytechnic, A*STAR Science Awardee

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