Immediate goals: To understand the gut-brain mechanisms controlling feeding and dietary decisions, as well as other motivated behaviours.
Ultimate goals: To generate new scientific knowledge which could optimise human health and potential and promote a sustainable society.
The zebrafish is a vertebrate that shares genes, physiology, gut-brain anatomy and behaviours with mammals, while at the same time being small and tractable enough to gain a holistic perspective of organ and brain function.
It is also cost-effective and amenable to high-throughput genetic and pharmacological screening studies, particularly at the larval stages.
Quantitative Behavioural Analysis
Whatever you can bring!
Shi Yan Ng (Institute of Molecular and Cell Biology, A*STAR)
Anand Andiappan (Singapore Immunology Network, A*STAR)
Johan Eriksson (Singapore Institute of Clinical Sciences, A*STAR)
Shyam Prabakhar (Genome Institute of Singapore, A*STAR)
Xiaodi Su and Laura Sutarlie (Institute of Materials Research and Engineering, A*STAR)
Sudipto Roy (Institute of Molecular and Cell Biology, A*STAR)
Suresh Jesuthasan (LKC Medicine, NTU)
Peter Torok (SCELSE, NTU)
Alvin Loo and Huang Dejian (Food Science and Technology, NUS)
Ajay Mathuru (Yale-NUS College)
Lena Ho (Duke-NUS)
Shubha Vij and Marie Tan (Aquaculture, Republic Polytechnic)
Katheline Hua (Aquaculture, James Cook University Singapore)
TRANSLATION AND APPLICATION
Although we are a basic research lab, we run a number of translational projects in the domains of human health (e.g. multi-omics studies on human cohorts), drug discovery, and aquaculture.
We continue to be interested in forming impactful collaborations with industry and clinical partners.