OUR RESEARCH

OUR GOALS

Immediate goals: To understand the gut-brain mechanisms controlling feeding and dietary decisions.

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Ultimate goals: To generate new scientific knowledge which could optimize human health and potential and promote a sustainable society.

WHY ZEBRAFISH?

The zebrafish is a vertebrate that shares genes, physiology, gut-brain anatomy and behaviours with mammals, while at the same time being small and tractable enough to gain a holistic perspective of organ and brain function. 

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It is also cost-effective and amenable to high-throughput genetic and pharmacological screening studies, particularly at the larval stages. 

OUR TECHNIQUES

• Functional Imaging

• Electrophysiology

• Quantitative Behavioural Analysis

• Circuit Manipulation 

• Omics Approaches

• Genetic Modeling 

• Pharmacological Screening

• Machine Learning

• Whatever you can bring! 

KEY COLLABORATORS

• Cheng Li (University of Alberta & Bioinformatics Institute, A*STAR)

• Suresh Jesuthasan (Nanyang Technological University - LKC Medicine)

• Peter Torok (Nanyang Technological University)

• Ajay Mathuru (Yale - National University of Singapore)

• Sudipto Roy (Institute of Molecular and Cell Biology, A*STAR)

• Shyam Prabakhar (Genome Institute of Singapore, A*STAR)

• Katheline Hua (James Cook University Singapore)

• Lena Ho (Duke - National University of Singapore)

TRANSLATION AND APPLICATION

Although we are a basic research lab, we also have a number of translational projects and collaborations in the domains of human health and aquaculture. 

We continue to be interested in forming impactful collaborations with industry and clinical partners.