OUR RESEARCH

IMG_20200103_114950-01-Biopolis1_edited.jpg

OUR GOALS

Immediate goals: To understand the gut-brain mechanisms controlling feeding and dietary decisions.

Ultimate goals: To generate new scientific knowledge which could optimize human health and potential and promote a sustainable society.

Zebrafish.jpeg

WHY ZEBRAFISH?

The zebrafish is a vertebrate that shares genes, physiology, gut-brain anatomy and behaviours with mammals, while at the same time being small and tractable enough to gain a holistic perspective of organ and brain function. 

It is also cost-effective and amenable to high-throughput genetic and pharmacological screening studies, particularly at the larval stages. 

AVG_OMPTRPC2andHuCGC6s.png

OUR TECHNIQUES

  • Functional Imaging

  • Electrophysiology

  • Quantitative Behavioural Analysis

  • Circuit Manipulation 

  • Omics Approaches

  • Genetic Modeling 

  • Pharmacological Screening

  • Machine Learning

  • Whatever you can bring! 

SJlab_NCommsjpg.jpg

KEY COLLABORATORS

  • Cheng Li (University of Alberta & Bioinformatics Institute, A*STAR)

  • Suresh Jesuthasan (Nanyang Technological University - LKC Medicine)

  • Peter Torok (Nanyang Technological University)

  • Ajay Mathuru (Yale - National University of Singapore)

  • Sudipto Roy (Institute of Molecular and Cell Biology, A*STAR)

  • Shyam Prabakhar (Genome Institute of Singapore, A*STAR)

  • Katheline Hua (James Cook University Singapore)

  • Lena Ho (Duke - National University of Singapore)

Barramundi_edited.jpg

TRANSLATION AND APPLICATION

Although we are a basic research lab, we also have a number of translational projects and collaborations in the domains of human health and aquaculture. 


We continue to be interested in forming impactful collaborations with industry and clinical partners.  

 
  • Twitter
  • LinkedIn

©2020 by Caroline Wee Lab