OUR RESEARCH
OUR GOALS
Immediate goals: To understand the gut-brain mechanisms controlling feeding and dietary decisions.
Ultimate goals: To generate new scientific knowledge which could optimize human health and potential and promote a sustainable society.
WHY ZEBRAFISH?
The zebrafish is a vertebrate that shares genes, physiology, gut-brain anatomy and behaviours with mammals, while at the same time being small and tractable enough to gain a holistic perspective of organ and brain function.
It is also cost-effective and amenable to high-throughput genetic and pharmacological screening studies, particularly at the larval stages.
OUR TECHNIQUES
Functional Imaging
Electrophysiology
Quantitative Behavioural Analysis
Circuit Manipulation
Omics Approaches
Genetic Modeling
Pharmacological Screening
Machine Learning
Whatever you can bring!
KEY COLLABORATORS
Cheng Li (University of Alberta & Bioinformatics Institute, A*STAR)
Suresh Jesuthasan (Nanyang Technological University - LKC Medicine)
Peter Torok (Nanyang Technological University)
Ajay Mathuru (Yale - National University of Singapore)
Sudipto Roy (Institute of Molecular and Cell Biology, A*STAR)
Shyam Prabakhar (Genome Institute of Singapore, A*STAR)
Katheline Hua (James Cook University Singapore)
Lena Ho (Duke - National University of Singapore)
TRANSLATION AND APPLICATION
Although we are a basic research lab, we also have a number of translational projects and collaborations in the domains of human health and aquaculture.
We continue to be interested in forming impactful collaborations with industry and clinical partners.